≥99% HPLCBatch testedIdentity by MS, purity by HPLC
Lot numberedCertificate filed per lot
Cold stored2 to 8 °C until dispatch
Matrixyl 3000
10mg lyophilised powderCAS 214047-00-4
A palmitoylated peptide combination used in skin-matrix and cosmetic-science research on collagen-related signalling and lipid-peptide behaviour.
£24.90per vial, VAT included
In stock, dispatched same day before 16:00
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- Batch certificate in the COA Database
Sold for research purposes only. For in-vitro laboratory research. Not a medicine and not for human or animal consumption. Supplied to qualified individuals aged 18 and over; you confirm this at checkout.
Research overview
Matrixyl 3000 is a trade-style name for palmitoylated peptide combinations used in cosmetic-science research. The specifications listed here, including the formula, weight and the synonym Palmitoyl-KTTKS, correspond to the palmitoyl pentapeptide component. It is studied in skin-matrix and collagen-related signalling. Supplied at 10mg as a lyophilised powder for in-vitro laboratory research only.
Palmitoyl-KTTKS pairs the pentapeptide Lys-Thr-Thr-Lys-Ser, a sequence derived from type I procollagen, with a palmitic acid chain that raises lipophilicity. The idea behind such matrikine peptides is that small fragments of matrix proteins may signal to fibroblasts that matrix is being broken down and that synthesis should increase. In fibroblast cultures, palmitoylated pentapeptides have been reported to raise collagen I, collagen III and fibronectin expression. Much of the supporting data comes from cosmetic-science and supplier studies rather than independent academic work.
Laboratory use includes fibroblast culture assays measuring collagen and fibronectin by ELISA or qPCR, skin-model permeation studies with Franz cells, and lipid-peptide behaviour in solution, including micelle and aggregation studies. It is also a model for how acylation changes solubility. It is supplied as a lyophilised powder in a 10mg vial, and solubility depends on the solvent chosen.
Research areas
- Fibroblast collagen and fibronectin expression
- Matrikine peptide signalling
- Skin-model permeation in Franz cells
- Lipid-peptide aggregation and micelle behaviour
- Effect of palmitoylation on solubility
Specifications
- CAS number
- 214047-00-4
- Molecular formula
- C39H75N7O10
- Molecular weight
- ~802.05 g/mol
- Form
- lyophilised powder
- Purity
- ≥99% (HPLC)
- Also known as
- Matrixyl, Palmitoyl Pentapeptide-4, Palmitoyl-KTTKS, PAL-Lys-Thr-Thr-Lys-Ser, Palmitoyl Pentapeptide-3
- Supplied as
- 10mg per vial, lyophilised powder
Storage and handling
Store the lyophilised powder cold, dry and protected from light, and let the vial reach room temperature before opening. Palmitoylated peptides are lipophilic, so test solubility on a small amount before choosing a laboratory diluent.
Certificates of analysis
Each lot of Matrixyl 3000 is released with a certificate recording identity and purity. Enter the lot number printed on your vial on the lab testing page to view it.
Questions
Which peptide do the listed specifications describe?
The formula, weight and synonyms on this page describe palmitoyl pentapeptide, Pal-KTTKS. The name Matrixyl 3000 has also been used for combinations of palmitoylated peptides, so check the analytical data for the batch you receive.
What form is it supplied in?
It is a lyophilised powder in a 10mg vial. Keep it cold, dry and away from light, and prepare solutions only when the material is needed.
Is Matrixyl 3000 a cosmetic or a medicine?
Neither. It is supplied strictly for in-vitro laboratory research. It is not a cosmetic product, medicine, food or supplement, and it is not for human or animal use. Buyers must be aged 18 or over.
