≥99% HPLCBatch testedIdentity by MS, purity by HPLC
Lot numberedCertificate filed per lot
Cold stored2 to 8 °C until dispatch
AHK-Cu
100mg lyophilised powderCAS 682809-81-0
A copper-binding tripeptide complex studied in metal-peptide coordination chemistry and copper-dependent cell signalling, often alongside GHK-Cu.
£33.90per vial, VAT included
In stock, dispatched same day before 16:00
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- Batch certificate in the COA Database
Sold for research purposes only. For in-vitro laboratory research. Not a medicine and not for human or animal consumption. Supplied to qualified individuals aged 18 and over; you confirm this at checkout.
Research overview
AHK-Cu is a copper(II) complex of the tripeptide Ala-His-Lys (AHK), also listed as Copper Tripeptide-3. It is studied in metal-peptide coordination chemistry and in copper-dependent cell signalling, often alongside GHK-Cu, using fibroblast cultures and spectroscopic copper-binding assays. Supplied at 100mg as a lyophilised powder for in-vitro laboratory research only.
In tripeptides of this type, the N-terminal amine, a backbone nitrogen and the histidine side chain are described as the copper-binding groups. The literature presents such copper-peptide complexes as carriers that can deliver the metal to cells and influence copper-dependent enzymes such as lysyl oxidase. Studies in fibroblast cultures report changes in the expression of collagen and other extracellular matrix genes. Published evidence for AHK-Cu itself is thinner than for GHK-Cu.
Laboratory use includes spectroscopic work on copper binding (UV-visible, circular dichroism and EPR), fibroblast and keratinocyte cultures with collagen, glycosaminoglycan and matrix metalloproteinase readouts, and copper-uptake assays. Comparison with GHK-Cu helps separate sequence effects from the shared copper-binding role. It is supplied as a lyophilised powder in a 100mg container.
Research areas
- Copper(II) coordination by Ala-His-Lys
- Copper uptake and delivery in cell cultures
- Collagen and matrix gene expression in fibroblasts
- Lysyl oxidase and other copper-dependent enzymes
- Comparison with GHK-Cu
Specifications
- CAS number
- 682809-81-0
- Molecular formula
- C15H26N6O4 (AHK peptide), copper(II) complex
- Molecular weight
- 354.41 g/mol (peptide); 451.39 g/mol (copper complex, monohydrochloride)
- Sequence
- Ala-His-Lys (AHK), copper(II) complex
- Form
- lyophilised powder
- Purity
- ≥99% (HPLC)
- Also known as
- AHK-Cu, Copper Tripeptide-3, L-Alanyl-L-histidyl-L-lysine copper(II) complex
- Supplied as
- 100mg per vial, lyophilised powder
Storage and handling
Store the lyophilised powder cold, dry and protected from light, with the container tightly closed. Avoid strong chelating agents when preparing solutions, since they can strip the copper from the peptide.
Certificates of analysis
Each lot of AHK-Cu is released with a certificate recording identity and purity. Enter the lot number printed on your vial on the lab testing page to view it.
Questions
How does AHK-Cu differ from GHK-Cu?
Both are copper(II) complexes of a tripeptide. AHK-Cu uses Ala-His-Lys and GHK-Cu uses Gly-His-Lys, so they differ by one residue at the N-terminus. They are often studied side by side.
How is AHK-Cu supplied and stored?
It is supplied as a lyophilised powder in a 100mg container. Keep it cold, dry and away from light, and prepare solutions only when the material is needed.
Is AHK-Cu a medicine?
No. It is supplied strictly for in-vitro laboratory research. It is not a medicine, food, supplement or cosmetic ingredient, and it is not for human or animal use. Buyers must be aged 18 or over.
Skin and matrix
Studied alongside
Skin and matrix
PTD-DBM
A cell-penetrating peptide built to interrupt a CXXC5-Dishevelled contact
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