Growth axis
CJC-1295 with DAC
A GHRH 1-29 analogue carrying a drug-affinity-complex modification for longer persistence
£20.902mg
≥99% HPLCBatch testedIdentity by MS, purity by HPLC
Lot numberedCertificate filed per lot
Cold stored2 to 8 °C until dispatch
Ipamorelin
5mg lyophilised powderCAS 170851-70-4
A selective secretagogue for growth hormone, used to study ghrelin-receptor (GHS-R1a) binding and signalling.
£15.52per vial, VAT included
In stock, dispatched same day before 16:00
- Free shipping on UK orders over £20.00
- Same day dispatch on orders placed before 16:00
- Batch certificate in the COA Database
Sold for research purposes only. For in-vitro laboratory research. Not a medicine and not for human or animal consumption. Supplied to qualified individuals aged 18 and over; you confirm this at checkout.
Research overview
Ipamorelin is a synthetic pentapeptide secretagogue, Aib-His-D-2-Nal-D-Phe-Lys with a C-terminal amide, also listed as NNC 26-0161. It is studied in vitro and in preclinical models for selective binding and signalling at the ghrelin receptor GHS-R1a. Supplied at 5mg as a lyophilised powder for in-vitro laboratory research only.
Ipamorelin is described in the literature as a selective agonist at GHS-R1a. In the original characterisation work it was reported to stimulate growth-hormone release in pituitary cell and animal models without the rise in ACTH or cortisol seen with some earlier secretagogues such as GHRP-6 and hexarelin. The peptide contains the non-proteinogenic residue Aib, which is thought to improve resistance to proteolysis.
Researchers use it as a selective reference ligand in receptor-binding and calcium assays, in hormone-release assays with primary pituitary cells, and in comparison studies against GHRP-2, GHRP-6 and hexarelin. Mass spectrometry work on Aib-containing peptides is another application, since the Aib residue changes fragmentation patterns. It is supplied as a lyophilised powder in a 5mg vial.
Research areas
- Selective GHS-R1a agonism
- Calcium and inositol phosphate signalling assays
- Pituitary cell hormone-release models
- Receptor selectivity compared with other secretagogues
- Aib-containing peptide stability and mass spectrometry
Specifications
- CAS number
- 170851-70-4
- Molecular formula
- C38H49N9O5
- Molecular weight
- ~711.85 g/mol
- Sequence
- Aib-His-D-2-Nal-D-Phe-Lys-NH2 (C-terminal amide; Aib = a-aminoisobutyric acid)
- Form
- lyophilised powder
- Purity
- ≥99% (HPLC)
- Also known as
- Ipamorelin, Ipamorelin Acetate, NNC 26-0161, Ipamorelin pentapeptide
- Supplied as
- 5mg per vial, lyophilised powder
Storage and handling
Store the lyophilised powder in a freezer, protected from moisture and light, and let the vial reach room temperature before opening. Reconstitute with an appropriate laboratory diluent and keep reconstituted material cold.
Certificates of analysis
Each lot of Ipamorelin is released with a certificate recording identity and purity. Enter the lot number printed on your vial on the lab testing page to view it.
Questions
What makes ipamorelin different from GHRP-6 and GHRP-2?
It is a shorter, five-residue peptide containing Aib and is described as more selective for GHS-R1a. Earlier hexapeptides such as GHRP-6 were reported to affect additional hormone axes in some models.
How is ipamorelin supplied?
It is supplied as a lyophilised powder in a 5mg vial. Keep it cold, dry and away from light, and reconstitute with a suitable laboratory diluent only when the material is needed.
Is ipamorelin a medicine?
No. It is supplied strictly for in-vitro laboratory research. It is not a medicine, food or supplement, and it is not for human or animal use. Buyers must be aged 18 or over.
Growth axis
Studied alongside
