Growth axis
CJC-1295 with DAC
A GHRH 1-29 analogue carrying a drug-affinity-complex modification for longer persistence
£20.902mg
≥99% HPLCBatch testedIdentity by MS, purity by HPLC
Lot numberedCertificate filed per lot
Cold stored2 to 8 °C until dispatch
GHRP-6
5mg lyophilised powderCAS 87616-84-0
A hexapeptide that releases growth hormone, used to study ghrelin-receptor (GHS-R1a) activation and neuroendocrine signalling.
£9.50per vial, VAT included
In stock, dispatched same day before 16:00
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- Same day dispatch on orders placed before 16:00
- Batch certificate in the COA Database
Sold for research purposes only. For in-vitro laboratory research. Not a medicine and not for human or animal consumption. Supplied to qualified individuals aged 18 and over; you confirm this at checkout.
Research overview
GHRP-6 is a synthetic hexapeptide, His-D-Trp-Ala-Trp-D-Phe-Lys with a C-terminal amide, described in the literature as an early member of the growth-hormone-releasing peptide class. It is studied in vitro for ghrelin-receptor (GHS-R1a) activation and neuroendocrine signalling. Supplied at 5mg as a lyophilised powder for in-vitro laboratory research only.
GHRP-6 binds GHS-R1a, a G protein-coupled receptor that was identified as the target of this peptide class before ghrelin itself was discovered. Receptor activation signals through Gq and phospholipase C, producing inositol phosphates and a rise in intracellular calcium. The literature also describes activity on appetite-related neurons in hypothalamic preparations and on ghrelin-receptor signalling outside the pituitary. Findings vary between models, so context matters when interpreting data.
In the laboratory it serves as a reference agonist in GHS-R1a binding and calcium-flux assays, in hormone-release assays with pituitary cultures, and in hypothalamic slice or neuronal culture work. Researchers also use it to study receptor internalisation and cross-talk with other G protein-coupled receptors. It is supplied as a lyophilised powder.
Research areas
- GHS-R1a binding and Gq signalling
- Inositol phosphate and calcium-flux assays
- Hypothalamic neuron and slice preparations
- Receptor internalisation and cross-talk
- Secretagogue structure-activity comparisons
Specifications
- CAS number
- 87616-84-0
- Molecular formula
- C46H56N12O6
- Molecular weight
- ~873.0 g/mol.
- Sequence
- His-D-Trp-Ala-Trp-D-Phe-Lys-NH2 (C-terminal amide)
- Form
- lyophilised powder
- Purity
- ≥99% (HPLC)
- Also known as
- GHRP-6, Growth Hormone Releasing Hexapeptide, His-D-Trp-Ala-Trp-D-Phe-Lys-NH2.
- Supplied as
- 5mg per vial, lyophilised powder
Storage and handling
Store the lyophilised powder cold, dry and protected from light, and allow the vial to reach room temperature before opening. Reconstitute with an appropriate laboratory diluent and keep reconstituted material cold.
Certificates of analysis
Each lot of GHRP-6 is released with a certificate recording identity and purity. Enter the lot number printed on your vial on the lab testing page to view it.
Questions
What is the difference between GHRP-6 and hexarelin?
Hexarelin is a close structural derivative of GHRP-6 in which the D-Trp residue carries a 2-methyl group. Both act at GHS-R1a, and they are often compared in receptor-binding and signalling studies.
How is GHRP-6 supplied and stored?
It is supplied as a lyophilised powder in a 5mg vial. Keep it cold, dry and away from light, and reconstitute with a suitable laboratory diluent only when the material is needed.
Is GHRP-6 a medicine?
No. It is supplied strictly for in-vitro laboratory research. It is not a medicine, food or supplement, and it is not for human or animal use. Buyers must be aged 18 or over.
Growth axis
Studied alongside
