Growth axis
CJC-1295 with DAC
A GHRH 1-29 analogue carrying a drug-affinity-complex modification for longer persistence
£20.902mg
≥99% HPLCBatch testedIdentity by MS, purity by HPLC
Lot numberedCertificate filed per lot
Cold stored2 to 8 °C until dispatch
Hexarelin
2mg lyophilised powderCAS 140703-51-1
A synthetic hexapeptide that stimulates growth hormone release, used to study GHS-R1a receptor binding and signalling.
£12.00per vial, VAT included
In stock, dispatched same day before 16:00
- Free shipping on UK orders over £20.00
- Same day dispatch on orders placed before 16:00
- Batch certificate in the COA Database
Sold for research purposes only. For in-vitro laboratory research. Not a medicine and not for human or animal consumption. Supplied to qualified individuals aged 18 and over; you confirm this at checkout.
Research overview
Hexarelin is a synthetic hexapeptide secretagogue, His-D-2-methyl-Trp-Ala-Trp-D-Phe-Lys with a C-terminal amide, listed as a GHRP-6 analogue. It is studied in vitro and in preclinical models for binding and signalling at the ghrelin receptor GHS-R1a. Supplied at 2mg as a lyophilised powder for in-vitro laboratory research only.
Hexarelin activates GHS-R1a and, like related secretagogues, raises intracellular calcium through Gq signalling. The literature also reports that it binds the scavenger receptor CD36 on cardiac and vascular cells, a property not shared by every peptide in this class. That has made it a tool for separating GHS-R1a-dependent from CD36-dependent signalling in cell and preclinical models, although the relative weight of each pathway is still debated.
Laboratory use includes receptor-binding and calcium assays in GHS-R1a-expressing cells, comparative studies against GHRP-2, GHRP-6 and ipamorelin, and cultured cardiomyocyte work on survival signalling pathways. Receptor desensitisation after repeated exposure is another recurring topic, as is the stability of the peptide in culture media over a working day. It is supplied as a lyophilised powder in a 2mg vial.
Research areas
- GHS-R1a binding and calcium signalling
- CD36 interaction in cardiac and vascular cell models
- Cardiomyocyte survival-pathway signalling
- Receptor desensitisation after repeated exposure
- Comparison with other hexapeptide secretagogues
Specifications
- CAS number
- 140703-51-1
- Molecular formula
- C47H58N12O6
- Molecular weight
- ~887.04 g/mol
- Sequence
- His-D-2-methyl-Trp-Ala-Trp-D-Phe-Lys-NH2 (C-terminal amide)
- Form
- lyophilised powder
- Purity
- ≥99% (HPLC)
- Also known as
- Hexarelin, Growth Hormone-Releasing Peptide-6 analogue, GHRP-6 analogue
- Supplied as
- 2mg per vial, lyophilised powder
Storage and handling
Store the lyophilised powder in a freezer, protected from moisture and light, and let the vial warm to room temperature before opening. Reconstitute with an appropriate laboratory diluent and keep reconstituted material cold.
Certificates of analysis
Each lot of Hexarelin is released with a certificate recording identity and purity. Enter the lot number printed on your vial on the lab testing page to view it.
Questions
How does hexarelin differ from GHRP-6?
Hexarelin is a close analogue of GHRP-6 with a 2-methyl group on the D-tryptophan residue. Both act at GHS-R1a, but the literature also reports CD36 binding for hexarelin.
How is hexarelin supplied?
It is supplied as a lyophilised powder in a 2mg vial. Keep it cold, dry and away from light, and reconstitute with a suitable laboratory diluent only when required.
Is hexarelin a medicine?
No. It is supplied strictly for in-vitro laboratory research. It is not a medicine, food or supplement, and it is not for human or animal use. Buyers must be aged 18 or over.
Growth axis
Studied alongside
