Adamax

Research overview

Adamax is a synthetic hexapeptide listed as an adamantane-modified acetyl peptide, also called Adamantyl Acetyl Hexapeptide. It is used in melanocortin-pathway signalling work and in peptide stability and structure-activity studies, where the bulky adamantane group is the variable of interest. Supplied at 5mg as a powder for in-vitro laboratory research only.

The adamantane group is a rigid, lipophilic, cage-like hydrocarbon. Attaching it to a peptide is a recognised strategy in peptide chemistry for raising lipophilicity and resistance to enzymatic breakdown, which can alter membrane interactions and persistence in assay media. Primary published literature on Adamax itself is limited, so the context here is general to adamantane-modified peptides and to melanocortin pathway research. Claims found elsewhere should be checked against peer-reviewed sources.

Laboratory work includes receptor-binding and cAMP assays in cells expressing melanocortin receptors, stability studies in serum-containing media by HPLC, and measurements of lipophilicity and solubility across solvents. It is also a convenient test case for structure-activity comparisons between modified and unmodified hexapeptides. It is supplied as a powder in a 5mg vial, and solubility should be checked on a small amount first.

Research areas

• Melanocortin receptor binding and cAMP assays
• Adamantane modification and lipophilicity
• Peptide stability in serum-containing media
• Structure-activity studies of modified hexapeptides
• Solubility profiling across laboratory solvents

Specifications

Molecular formula

C50H69N11O11S

Molecular weight

1032.24 g/mol

Form

powder

Purity

≥99% (HPLC)

Also known as

Adamax, Adamantyl Acetyl Hexapeptide, Adamantane-modified acetyl hexapeptide

Supplied as

5mg per vial, powder

Storage and handling

Store the powder cold, dry and protected from light, and let the vial reach room temperature before opening. Because the adamantane group is lipophilic, test solubility on a small amount before choosing a laboratory diluent.

Certificates of analysis

Each lot of Adamax is released with a certificate recording identity and purity. Enter the lot number printed on your vial on the lab testing page to view it.

Questions