≥99% HPLCBatch testedIdentity by MS, purity by HPLC
Lot numberedCertificate filed per lot
Cold stored2 to 8 °C until dispatch
Vesugen
20mg lyophilised powder
A three-residue bioregulator-type peptide studied in vascular endothelial cell proliferation and survival models.
£39.90per vial, VAT included
In stock, dispatched same day before 16:00
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- Same day dispatch on orders placed before 16:00
- Batch certificate in the COA Database
Sold for research purposes only. For in-vitro laboratory research. Not a medicine and not for human or animal consumption. Supplied to qualified individuals aged 18 and over; you confirm this at checkout.
Research overview
Vesugen is a three-residue bioregulator-type peptide, Lys-Glu-Asp (KED). It is studied in vascular endothelial cell proliferation and survival models, using cultured endothelial cells, within the family of very short peptides described largely by the Khavinson group. Supplied at 20mg as a lyophilised powder for in-vitro laboratory research only.
Vesugen is described as the vascular-associated tripeptide of the family. It is proposed to enter endothelial cells and interact with DNA or chromatin proteins, shifting the expression of genes that control growth and survival. In endothelial cell cultures, reports describe effects on proliferation, on markers of cell senescence and on stress responses. The studies come from a small number of laboratories, and the underlying mechanism remains a hypothesis.
Laboratory work uses endothelial cell lines such as HUVEC, with proliferation and viability assays, tube-formation assays, senescence staining and qPCR of vascular genes. Labelled analogues are used for uptake studies, and the stability of a three-residue peptide in culture media is followed by HPLC. It is supplied as a lyophilised powder in a 20mg vial.
Research areas
- Endothelial cell proliferation and survival
- Tube-formation assays
- Senescence staining in vascular cells
- Vascular gene expression by qPCR
- Tripeptide uptake and stability
Specifications
- Molecular formula
- C15H26N4O8
- Molecular weight
- 390.39 g/mol
- Sequence
- Lys-Glu-Asp (KED)
- Form
- lyophilised powder
- Purity
- ≥99% (HPLC)
- Also known as
- Vesugen; KED; Lys-Glu-Asp
- Supplied as
- 20mg per vial, lyophilised powder
Storage and handling
Store the lyophilised powder in a freezer, protected from moisture and light, and let the vial reach room temperature before opening. Reconstitute with an appropriate laboratory diluent and keep reconstituted material cold.
Certificates of analysis
Each lot of Vesugen is released with a certificate recording identity and purity. Enter the lot number printed on your vial on the lab testing page to view it.
Questions
How is Vesugen related to Vilon?
Vilon is the dipeptide Lys-Glu, and Vesugen is the tripeptide Lys-Glu-Asp, so Vesugen extends Vilon by one aspartate residue. They are studied in different cell types.
How is Vesugen supplied and stored?
It is supplied as a lyophilised powder in a 20mg vial. Keep it cold, dry and away from light, and reconstitute with a suitable laboratory diluent only when the material is needed.
Is Vesugen a medicine?
No. It is supplied strictly for in-vitro laboratory research. It is not a medicine, food or supplement, and it is not for human or animal use. Buyers must be aged 18 or over.
